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Contents

  • Laboratory Analyses
  • Quality Control Analyses
  • Scientific R&D Analyses

(1) Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J. and Oesser, S. (2014). Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacol. Physiol., Vol 27, Iss. 3, 113-119.

(2) Choi, S.Y., Ko, E.J., Lee, Y.H., Kim, B.G., Shin, H.J., Seo, D.B., Lee, S.J., Kim, B.J. and Kim, M.N. (2013). Effects of collagen tripeptide supplement on skin properties: A prospective, randomized, controlled study. Journal of Cosmetic and Laser Therapy.


(3) Kantor, I., Donikyan, L.A., Simon, E. And Wollschlaeger, B. (2002). Results of a study evaluating the use of a dietary supplement formula in the management of age-related skin changes in women with moderate to severe wrinkling of the periorbital area. The Journal of the American Nutraceutical Association, Vol. 5, Iss. 2, 10-19.


(4) Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V. and Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacol. Physiol., Vol. 27, Iss. 1, 47-55.


(5) Ohara, H., Ito, K., Iida, H. And Matsumoto, H. (2009). Improvement in the moisture content of the stratum corneum following 4 weeks of collagen hydrolysate ingestion. Nippon Shokuhin Kagaku Kogaku Kaishi (J. Soc. Food Sci. Technol.) Vol. 56, Iss. 3, 137-145.

(6) Kumar, P., Nagarajan, A., & Uchil, P. D. (2018). Analysis of cell viability by the MTT assay. Cold springharbor protocols, 2018(6), pdb-prot095505.

Liang, C. C., Park, A. Y., & Guan, J. L. (2007). In vitro scratch assay: a convenient and inexpensivemethod for analysis of cell migration in vitro. Nature protocols, 2(2), 329-333.

(7) Rice-Evans, C. A. (2000). Measurement of total antioxidant activity as a marker of antioxidant status in vivo: procedures and limitations. Free Radical Research, 33, S59-66.

(8) Palmieri, B., & Sblendorio, V. (2009). Current status of measuring oxidative stress. In Advanced Protocols in Oxidative Stress II (pp. 3-17). Totowa, NJ: Humana Press.

(9) McComiskey, K. P., & Tajber, L. (2018). Comparison of particle size methodology and assessment of nanoparticle tracking analysis (NTA) as a tool for live monitoring of crystallisation pathways.

(10) EuropeanJournal of Pharmaceutics and Biopharmaceutics, 130, 314-326.

(11) Khehra, N., Padda, I. S., & Swift, C. J. (2023). Polymerase chain reaction (PCR).

(12) Zhou, H., Tan, Y., & McClements, D. J. (2023). Applications of the INFOGEST in vitro digestion model to foods: A review. Annual Review of Food Science and Technology, 14(1), 135-156.

(13) Mahmood, T., & Yang, P. C. (2012). Western blot: technique, theory, and trouble shooting. North American journal of medical sciences, 4(9), 429.

(14) Visse, R., & Nagase, H. (2003). Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circulation research, 92(8), 827-839.

(15) Gu, H., Jasbi, P., Patterson, J., & Jin, Y. (2021). Enhanced detection of short‐chain fatty acids usinggas chromatography mass spectrometry. Current protocols, 1(6), e177.

(16) Marques, S., Trevisan, T., Maia, C., Breuer, A., & Owen, R. W. (2018). Improved methods for the rapidformation and prevention of advanced glycation end products (AGEs) in vitro by coupling to thehypoxanthine/xanthine oxidase assay system. Biomedicines, 6(3), 88.

Laboratory Analyses

As a leading company, we conduct comprehensive quality control and R&D analyses to verify the reliability, quality, and scientific foundation of our products. Our products are evaluated in accordance with national and international standards from the raw material acceptance stage to final product release.

Quality Control Analyses


All our products are evaluated and their compliance is verified through analyses conducted in our quality control laboratory and independent accredited laboratories.


Microbiological Safety Analyses


• E. coli

• Salmonella spp.

• Staphylococcus aureus
• Total aerobic bacterial count
• Yeast and mold analyses
• Coliform analyses
• Production environment hygiene controls
• Personnel hygiene and environmental monitoring tests


Physical and Chemical Quality Controls


• Capsule uniformity tests

• Disintegration and dissolution analyses
• Determination of moisture and water activity
• pH analyses
• Heavy metal analyses
• Active ingredient quantity verifications
• Nutritional value analyses


Contamination and Safety Analyses


• Pesticide residue analyses

• Mycotoxin analyses
• Solvent residue analyses
• Nitrate and nitrite analyses


Advanced Technology Verification Analyses


• Liposomal encapsulation verification analyses

• Probiotic viability analyses
• Nanoparticle characterization analyses (NTA)
• FTIR spectroscopic analyses


Scientific R&D Analyses


The biological efficacy of our products is scientifically investigated by our R&D team and academic collaborations using cell culture models and advanced analysis methods; the findings are published in international peer-reviewed journals.


Cell Culture Studies


• MTT cell viability analyses
• Cytotoxicity evaluations
• Scratch (wound closure) analyses
• Cell migration and proliferation analyses
• Apoptosis analyses


Molecular Biology Analyses


• PCR analyses
• RT-qPCR gene expression analyses
• Western Blot protein expression analyses

• SDS-PAGE protein characterization studies

Oxidative Stress and Antioxidant Capacity Analyses


• TAS (Total Antioxidant Status)
• TOS (Total Oxidant Status)
• Total antioxidant capacity analyses
• Free radical scavenging capacity analyses

Aging and Tissue Biology Analyses


• AGE (advanced glycation end products) inhibition analyses
• Collagen synthesis analyses
• MMP (matrix metalloproteinase) inhibition analyses
• Tissue biology and cellular aging studies


Nanotechnology and Bioavailability Analyses


• Bioaccessibility evaluations

• TEM (Transmission Electron Microscopy) imaging analyses
• Nanoparticle Tracking Analysis (NTA)

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