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Vitaminler ve Mineraller

What Are EPA and DHA? What Do They Do?

Prof. Dr. Hasan Altun
EPA ve DHA Nedir? Ne İşe Yarar?

EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are two important components among omega-3 fatty acids. EPA and DHA are found especially in fish and seafood and play roles in different physiological functions in the body. EPA is more associated with eicosanoid metabolism and inflammation-related processes, while DHA is particularly associated with the structure of the brain and retina. In this article, we address the questions: What is EPA? What is DHA? What do EPA and DHA do? What is the difference between them? And how should the daily EPA-DHA requirement be evaluated?

 What Is EPA (Eicosapentaenoic Acid)?

EPA is a long-chain omega-3 fatty acid found in cold-water fish. Chemically, it contains 20 carbon atoms and 5 double bonds. EPA affects many biological functions in the body and is generally known for regulating inflammatory processes. The human body does not produce EPA, so it must be obtained from external food sources. One of the most important functions of EPA is protecting vascular health. It helps in the production of compounds called prostaglandins and eicosanoids. These compounds dilate blood vessels by reducing inflammation in the body and support healthy blood flow. Especially when answering the question of what EPA and DHA are, one of the first things that comes to mind is how these two fatty acids support heart health. EPA has a significant effect on lowering bad cholesterol (LDL) and preventing atherosclerosis. It also shows positive effects on mental health. It can help cope with depression, anxiety, and stress.

 What Does EPA Do?

While EPA performs many biological functions the body needs, it is best known for its positive effects on heart health and the immune system. When asked what EPA does, its role in preventing cardiovascular diseases comes to the fore. EPA dilates blood vessels and improves blood flow, thereby reducing the risk of heart attack, stroke, and other cardiovascular diseases. Also, since this fatty acid has anti-inflammatory properties, it is used in the treatment of inflammation-related diseases such as arthritis. 

EPA and DHA are also quite important for supporting brain health. These fatty acids regulate the functions of brain cells and support mental health. They also play an important role in the treatment of mental disorders such as depression and anxiety. However, EPA's function of supporting heart health is most striking, and for this reason, EPA supplements are generally used to prevent cardiovascular diseases.

Where Is EPA Found?

Since EPA cannot be produced naturally in the body, it must be obtained from external food sources. The sources where EPA is found the most are cold-water fish and seafood. Fish such as salmon, mackerel, and sardines are extremely rich in EPA. Besides these, krill oil and fish oil capsules are also good options for providing EPA supplementation. Also, it is known that EPA is found in low amounts in some plant sources. To understand the answer to the question of what EPA is in more detail, it will be useful to examine these food sources. Consuming these sources regularly helps meet the body's daily EPA requirement. Especially for individuals who do not consume fish, fish oil supplements can support EPA intake. Besides fish oil, omega-3 supplements obtained from some algae can also be used to meet the EPA requirement. Foods rich in EPA:

  • Salmon
  • Mackerel
  • Sardines
  • Herring
  • Tuna
  • Sea bass
  • Krill oil
  • Fish oil capsules

Consuming these foods a few times a week significantly increases EPA and DHA intake.

 What Is DHA (Docosahexaenoic Acid)?

DHA is one of the most important omega-3 fatty acid types for brain and eye health. Chemically, DHA contains 22 carbon atoms and 6 double bonds. A large part of the human brain and eye retina consists of DHA, so the importance of DHA is very great especially in terms of brain functions and visual health. DHA supports cognitive functions by increasing the communication of brain cells.

Discussions on what DHA and EPA are are mostly related to the effects of these two fatty acids on brain development and the nervous system. DHA helps not only brain development but also the proper functioning of the central nervous system. Also, it is necessary to ensure the healthy functioning of the retinal cells in the eyes. DHA is especially important for supporting brain and nervous system health during critical developmental periods such as pregnancy and childhood. Also, it is known that DHA also has a positive effect on heart health.

What Does DHA Do?

DHA is an omega-3 fatty acid that strengthens nervous system health and improves brain functions. In the answer to the question of what DHA is, the effect of this fatty acid on the brain is the most striking feature. DHA supports the production of basic compounds found in the functional structures of the brain and required to provide communication. In this way, cognitive functions such as learning, memory, and concentration are protected. Especially for children, DHA supplementation is very important for brain development. Another important function of DHA is its contributions to visual health. A large part of the cells in the eye retina consists of DHA, and this fatty acid is necessary for the proper functioning of the sense of sight. Also, DHA is necessary to protect the health of the mother and baby during pregnancy and breastfeeding. During pregnancy, DHA supports the baby's brain development and can reduce the risk of premature birth. Especially fish oil supplements for children are quite useful for supporting DHA intake.

 In Which Foods Is DHA Found?

DHA is generally obtained from fish in the body, but some plant sources can also help in obtaining this fatty acid. DHA is found in high amounts especially in cold-water fish and seafood. Seafood such as salmon, herring, sardines, and tuna are the best sources of DHA. Also, there are supplements obtained from algae containing DHA, and these supplements form an ideal alternative for vegan and vegetarian individuals. Egg yolk is also rich in DHA, but it is found more especially in omega-3 enriched eggs. Regular fish consumption provides DHA and EPA intake in the most efficient way. Foods rich in DHA:

  • Salmon
  • Herring
  • Tuna
  • Mackerel
  • Algae oils (for vegans)
  • Egg yolk 

What Is the Daily EPA and DHA Requirement?

After the question of what EPA and DHA are, knowing the daily amounts that need to be taken is quite important to use the health benefits of these fatty acids in the most efficient way. Health professionals have determined the daily EPA and DHA amounts that need to be taken according to age, gender, and health condition. It is recommended that the daily EPA and DHA intake of adults be a total of 250–500 mg. However, for those at risk of heart disease, this amount can go up to 1000 mg. The recommended DHA amount for pregnant and breastfeeding women is 300–600 mg per day. Fish oil supplements for children should be between 100–250 mg according to age. Since DHA is critical for supporting brain development, it is very important to obtain this fatty acid in sufficient levels, especially during pregnancy and childhood.

EPA and DHA Benefits

EPA and DHA provide countless benefits in the body. The main benefits of these fatty acids are as follows:

  • Improves heart health: Protects blood vessels, regulates blood pressure, and lowers bad cholesterol.
  • Strengthens brain functions: Improves memory, learning, and concentration.
  • Strengthens the immune system: Reduces inflammation and protects the body against diseases.
  • Supports visual health: Strengthens retinal cells and protects visual functions.
  • Improves skin health: Provides a healthy skin appearance by reducing inflammation in the skin.
  • Balances mood: Can reduce depression and anxiety.

You can examine the omega 3 formula where the EPA and DHA amounts are stated transparently.

In conclusion, EPA and DHA are indispensable nutrients for protecting both physical and mental health. Consuming seafood regularly or taking quality fish oil supplements ensures that these important fatty acids are obtained in sufficient levels. Especially in childhood, pregnancy, and advanced age periods, EPA and DHA support is of great importance for long-term health.

Sources

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